Human-induced Megakaryocytes-derived Exosomes
TempoOmes™-iMK
Harnessing Platelet‑Linked Biology
Human induced megakaryocytes (iMKs) are megakaryocyte‑like cells generated from Tempo’s proprietary human iPSC platform, rather than isolated directly from donor tissues.
Megakaryocytes are large, specialized hematopoietic cells that give rise to platelets and are characterized by an active secretory profile and rich vesicle production, making them a valuable source of bioactive exosomal cargo.
Megakaryocytes are large, highly specialized cells found in the bone marrow that give rise to platelets and contribute to the regulation of vascular and tissue homeostasis. Biologically, they are characterized by an active secretory profile and the ability to release extracellular vesicles enriched in growth factors, peptides, and other signaling molecules. This makes megakaryocyte-derived exosomes an attractive, human‑relevant source of bioactive “cargo” for exploring next‑generation, science‑driven product concepts.
SKU: 2210pc
Nanoparticle Tracking Analysis (NTA) system uses a fluorescent molecule to track exosomes released by the TempoOmes™-iMK cells in real-time: size distribution: 136 +/- 2.2 nm; 94.57 +/- 0.50 particles/frame.
Human induced megakaryocytes (iMKs)
Human induced megakaryocytes (iMKs) are megakaryocyte‑like cells generated from Tempo’s proprietary human iPSC platform, rather than isolated directly from donor tissues. Megakaryocytes are large, specialized hematopoietic cells that give rise to platelets and are characterized by an active secretory profile and rich vesicle production, making them a valuable source of bioactive exosomal cargo.
High-purity and bioactive
Biotech-made ingredient
Clean-label and bio-identical
Sustainable. Ethical.
Non-animal derived supply
At Tempo, by utilizing our unique in-house developed proprietary human inducible pluripotent stem cell (iPSC) technology, we eliminate the need for primary human tissue harvesting while maintaining high-purity and sustainably manufactured alternatives to traditional biologicals. We precisely direct the iPSCs into specialized lineages, such as induced Megakaryocytes (iMKs), to curate a specific, potent ‘cargo’ of exosomal growth factors and peptides. Our controlled manufacturing process produces a standardized, non-animal derived, ethically sourced supply of high-performance biologics.
- ◼ 14%
- ◼ 7.2%
- ◼ 6.5%
- ◼ 5.3%
- ◼ 5.2%
- ◼ 61.8%
Exosomes as a High‑Potential Platform for Next‑Generation Personal Care
Scalable, Custom-Built Bio-Manufacturing
Partner with Tempo to standardize lab-made biomanufactured ingredients!
In addition to our core portfolio, Tempo provides a scalable platform for co‑developing bespoke human cell–based solutions with product development teams. By leveraging our proprietary iPSC technology, we can engineer targeted cell lineages and exosomal profiles aligned with your specific formulation and performance objectives. Whether you are exploring a distinct exosomal cargo or a specialized cell type, our lab‑to‑scale biomanufacturing approach offers a sustainable, high‑purity path to differentiated, next‑generation products.
SKU: 2211pc
Produced in a biotechnology laboratory facility in the United States, we employ advanced Multi-Omics technologies to characterize and validate exosome contents, providing scientific data and quality documentations for formulation scientists. These exosomes offer formulation flexibility to support innovative product development in the personal care industry.
Target cellular aging → Skin damage and dermal aging
Stimulate and restore health of cells
Reduce inflammatory reactions