Human-induced Mesenchymal-derived Exosomes

TempoOmes™-iMC

Renewable, Human‑Relevant Biology

Human induced mesenchymal stem cells (iMSCs) are mesenchymal‑like cells generated from Tempo’s proprietary human iPSC platform, rather than isolated directly from donor tissues.

Mesenchymal stem cells are non‑hematopoietic, multipotent stromal cells that can differentiate into multiple lineages (including osteoblasts, chondrocytes, myocytes, and adipocytes) and are known for their immunomodulatory features and rich secretome.

Tempo‑iMSC™ cells express key MSC‑associated surface markers such as CD73, CD90, CD166, and CD105, alongside pluripotency markers Oct4 and Nanog—an expression profile associated with robust, long‑term proliferative capacity in cultured human MSCs. This combination supports scalable expansion and consistent phenotype, making Tempo‑iMSCs a dependable upstream source for exosome production.

SKU: 2209pc

Nanoparticle Tracking Analysis (NTA) system uses a fluorescent molecule to track the exosomes secreted by the TempoOmes™-iMSC cells in real-time: size distribution: 172 +/- 2.8 nm; 101.94 +/- 1.38 particles per frame.

Human-induced Mesenchymal (iMCs)

Because Tempo‑iMSC™ are derived using an in‑house, serum‑free, virus‑free, nucleic‑acid–free, feeder‑free, and integration‑free iPSC technology (starting from human dermal fibroblasts), they offer a highly controlled, human‑relevant cell model. Their ability to self‑renew and secrete cytokines, immune receptors, and other biomolecules makes them suitable for a wide range of research applications, including screening biologics and small molecules, high‑content imaging, biomarker discovery, cytotoxicity and investigative toxicology assays. And, they serve as a strong foundation for generating well‑characterized, information‑rich exosomes for innovative Personal Care formulations.

High-purity and bioactive

Biotech-made ingredient

Clean-label and bio-identical

Sustainable. Ethical.

Non-animal derived supply

At Tempo, by utilizing our unique in-house developed proprietary human inducible pluripotent stem cell (iPSC) technology, we eliminate the need for primary human tissue harvesting while maintaining high purity and sustainable manufacturing. We precisely differentiate the iPSCs into targeted lineages, such as induced Mesenchymal Stem Cells (iMSCs), to capture the specialized properties of the cell type and what its exosomes carry in as their cargo. Our overall manufacturing process ensures a sustainable, ethical, and non-animal derived supply of growth factors and peptides.

Using Protemics and Mass Spectrometry, PG.ProteinGroups were quantified according to Biological Processes and Molecular Functions. Pie chart shows PG.ProteinGroups by representation (%).
  • ◼ 23.1%
  • ◼ 8.7%
  • ◼ 23.1%
  • ◼ 8.7%
  • ◼ 23.1%
  • ◼ 55.8%

Exosomes as a High‑Potential Platform for Next‑Generation Personal Care

Scalable, Custom-Built Bio-Manufacturing

Partner with Tempo to standardize lab-made biomanufactured ingredients!

In addition to our core portfolio, Tempo provides a scalable platform for co‑developing bespoke human cell–based solutions with product development teams. By leveraging our proprietary iPSC technology, we can engineer targeted cell lineages and exosomal profiles aligned with your specific formulation and performance objectives. Whether you are exploring a distinct exosomal cargo or a specialized cell type, our lab‑to‑scale biomanufacturing approach offers a sustainable, high‑purity path to differentiated, next‑generation products.

SKU: 2211pc

Discuss Formulation Options

Produced in a biotechnology laboratory facility in the United States, we employ advanced Multi-Omics technologies to characterize and validate exosome contents, providing scientific data and quality documentations for formulation scientists. These exosomes offer formulation flexibility to support innovative product development in the personal care industry.

Target cellular aging → Skin damage and dermal aging

Stimulate and restore health of cells

Reduce inflammatory reactions